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H. Shaw Warren MD

Physician, Pediatrician, Infectious Disease Unit, Massachusetts General Hospital Associate Professor, Harvard Medical School

MEC Member: N/A 

Email: warren@helix.mgh.harvard.edu

Dr. Warren is a physician and pediatrician at Massachusetts General Hospital in Boston and an Associate Professor at Harvard Medical School. He is a member of the Medical and Scientific Staff of the Shriners Burns Institute and an associate faculty member of the Wyss Institute in Boston. Shaw attended Harvard College and Harvard Medical School. After training in internal medicine, he obtained further training in Infectious Disease at the Beth Israel Hospital and the Dana Farber Cancer Center in Boston before moving to Paris as a Fulbright fellow where he worked for three years in the department of Experimental Immunotherapy at the Institute Pasteur. Following this time, he returned to the Massachusetts General Hospital in the Infectious Disease Unit, where has worked since 1987.

Dr. Warren’s research interest has been in the area of bacterial infections, host response and inflammation. His laboratory has focused on basic science and analysis of clinical studies of inflammation induced by infection. In 2013 he reported data suggesting that the acute inflammatory response of mice differs markedly from that of humans, a finding that has substantial implications for drug development. He is director of SPIRIT (Species Inspired Research for Innovative Treatments), a multi-institutional program whose overarching goal is to discover better approaches for drug development based upon differences in the ways that species respond to pro-inflammatory challenge. Most recently Dr. Warren has started to explore novel approaches using physical energy to kill microorganisms in tissues. Dr. Warren was a co-founder of Critical Therapeutics (CRTX), Cidara (CDTX) and Setpoint Medical, Inc.