Gary gave an illuminating talk on the remarkable imaging technologies that he has developed with the purpose of seeing every single cell in the human body. These new and imaginative technologies run the gamut from in vivo tissue and cell imaging all the way to molecular imaging in vivo. The most remarkable technologies that Gary has developed include Optical Coherence Tomography (OCT) which allows the observer to develop 3-D images of functioning coronary arteries at high resolution, allowing definition of vulnerable plaques for example. This new technology has already been used to great effect in over 5 million patients. Gary also described ultrasound-based imaging that allows 3-D reconstruction of the esophagus and is assisting in the diagnosis of the premalignant condition Barrett’s Esophagus. Advances further into the microscopic scale include micro-OCT and Spectrally Encoded Confocal Microscopy that allows real time 3-D imaging of single cells in the body and has been put to use in diagnosing eosinophilic esophagitis and understanding the movement of cilia in the trachea. Gary clearly demonstrated his ability to take an amazing understanding of optics and physics into imaging human cells in vivo and onward to medical devices that help in rapid and less invasive diagnostic procedures.